This makes damage per second drop to 80%. The attack can be released only when fully charged. On my previous version of this guide, I made the mistake of assuming nobody would need a version that just had everything, since various wikis already have that. Using it with less than 5 coins does nothing, UNLOCK: Unlock this item by collecting 99 coins then spending all of them in the same run, Item Pool: Item Room, Greed Mode Item Room, Upon use, grants use of Brimstone for the current room, If used twice in the same room, the brimstone laser becomes massive and deals +1.8 more damage, Using it more than twice in the same room will give a damage increase each time. They can be used to damage enemies, Saturnus tears can't break objects such as poop and TNT barrels, Isaac now shoots ice tears that slow enemies. achievement (collect 50 items in a single run), X-Lax - Spawns a pool of slippery brown creep beneath Isaac, Experimental Pill - Increases one random stat and decreases another random stat. . arrow, Causes your friendly blue spiders and flies to become bigger and do x2 more damage, Allows Mom's Wig to spawn a maximum of 10 spiders at once instead of 5, Fly and spider familiars become stronger similar to BFFS, * shop room pool, shop item pool, blue, fat, Two items now spawn after beating a boss fight and the boss rush, however only one can be taken, The additional item will pick from the Boss Item Pool, Unlocked by donating to the donation machine in the shop, UNLOCK: Unlock this item by donating 50 pennies to the Shop, * shop room pool, shop item pool, white, question mark, square, theres options, * shop room pool, shop item pool, purple, paper, ticket, Isaac can now hold 2 cards or runes at once. rocks), Item Pool: Item Room, Devil Room, Greed Mode Devil Room, * item room, treasure room, item room pool, luigi board, weeja board, paper, grown, Automatically gives you 1 bar of charge after using your spacebar item, Fully recharges your current spacebar item when picked up, Any items which are normally a 1 room recharge are now timed instead, * shop room pool, shop item pool, battery, black, brown, When Isaac takes damage, the dead bird will spawn and attack nearby enemies in the current room for 2 damage per tick, * item room, treasure room, item room pool, the lost item pool, starting, grey, gray, Tears are replaced with the ability to charge and fire a powerful laser that travels in a straight line across the room, dealing a lot of damage (tear damage hits for 9 ticks per laser) to any enemies it comes into contact with, Does not directly affect your Damage stat but hits enemies 9 times per charge, Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others, If you somehow manage to get a second Brimstone, the laser becomes massive and deals double damage, * devil pool, devil room pool, devil deal, infinity, red, black, Has a chance to drop while playing any Blood Donation machine, UNLOCK: Unlock this item by playing the Blood Donation machine 30 times, Item Pool: None (Blood Donation machine only), Gives you a high rate of fire in exchange for a damage down, * secret room pool, item room, treasure room, item room pool, Thin Odd Mushroom, brown, purple, grey, gray, REPENTANCE - Odd Mushroom (thick) is now a larger damage increase (equal to that of Steven/Pentagram), but now also a larger speed downgrade (from -0.1 to -0.2), * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick, When you only have half a red heart remaining or less, you enter a curse state which adds +1.5 damage and +0.3 speed, When playing as Eve, this item activates with one FULL heart remaining or less AND also removes her 0.75 damage multiplier, raising it up to 1.0, The effect is permanently active for characters with no red hearts (e.g. If picked up by Cain, it shoots blood tears and the damage becomes increased to 5 (instead of the usual 3.5), UNLOCK: Unlock this item by beating the Dark Room with Cain, * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green cain and abel cain & abel, UNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards), * item room, treasure room, item room pool, bloody, silver, grey, gray, sharp, Item Pool: Item Room, Secret Room, Bomb Beggar, * secret room pool, item room, treasure room, item room pool, smile, face, grinning, doitfgt, REPENTANCE - The list of possible tear effects was updated in Repentance, to include all missing and new ones, * item room, treasure room, item room pool, pink note, money, cash, three dollar bill, Based on the Steam Workshop mod created by Amethyst, UNLOCK: Unlock this item by using 5 Gulp! Most items that change tear color will also give Brimstone an exotic appearance, but they do not combine and only one color effect is shown. Increasing tears stat will increase damage and width brimstone as well. By Travis Ward. Magic Fingers ignores the +40 flat damage with Ipecac, removing the synergy between these two, * shop room pool, shop item pool, item room, treasure room, item room pool, tissue, Isaac James Blood. poop, When used, you have a 50% chance to double all items, consumables and chests in the current room, If the effect fails, all pickups and items are deleted and Crooked Penny spawns 1 coin, If there are no consumables currently on the floor, Crooked Penny spawns 1 coin, This item works with items which can be purchased such as shop items, allowing you to spawn a free version if the effect triggers, If used in a shop and the effect fails, a Restock box can be used to restore the shop items. Las lgrimas del ojo izquierdo tienen un aumento plano de + 1 Dao, + 5 Rango y 0.5 de altura de lgrima. Isaac's head will remain stationary and fire tears. white, red, moms eye, mom eye, When used, drops a pool of 'lemonade' on the floor which damages any enemies that come into contact with it for 8 damage per tick, * item room, treasure room, item room pool, yellow, chet lemon, Gives Isaac an orbiting fly which deals 5 contact damage to enemies per tick, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, yellow book how to, * boss room pool, boss room item, bone, red, brown, Gives Isaac a random tarot card when picked up, * boss room pool, boss room item, eight, grey, gray, Drops 4 random pills on the floor around Isaac, Item Pool: Shop, Boss Room, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, shop room pool, shop item pool, bag, pouch, moms coin purse, mom coin purse. Trinkets Publicado por . This is shown by the Azazel skin spreading on Isaac's face, After 4 rooms, Isaac's face will flash red. The chance for a Red Room to unlock increases as you pick up more Crystal Keys. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. Binding of Isaac: Rebirth Wiki is a FANDOM Games Community. The number of burst tears is random between 6-11 and they have equal chance. While solid sulfur is yellow, molten sulfur is blood red. 3 keys = 25% chance. The bigger beam granted by double Brimstone synergizes with other items as expected. Deflected tears turn into homing tears and fire back at enemies, dealing 2 damage. Brimstone Blood laser barrage. 5.100.229 Unlocked from Challenge #24 - PAY TO PLAY, Friends till the end - Spawns three friendly blue attack flies, Infested! If the heart is hit, Isaac will take damage, Most enemies will target the heart over Isaac himself, Blood donation machines and devil beggars can be used for free. It gives you 2 seconds to pick it up again to re-heal, before it disappears, UNLOCK: Unlock this item by defeating Delirium as Tainted Magdalene, Whenever you deal damage to an enemy, has a chance to give the effect of one of Tainted ??? One of the sounds lasers can make when synergizing with Monstro's Lung. achievement (complete a victory lap, defeating the lamb boss), Horf! Item pedestals will cycle between two different items, allowing players to pick the one they want. If you have varicose veins, warning signs of a DVT include: A vein that bulges out and does not flatten when you lay flat or raise your leg. EDIT: NL now has Dead God, items are no longer bolded. 10 Eye of the Occult Item Effect: +1 Damage, +2 Range, -0.16 Shot Speed, and tears become controllable They can also make you feel weak, numb, dizzy, or confused. This is a one-time use of the Red Key item. This works with all normal pickups, including cards, runes, chests and trinkets. Does not prevent Isaac from taking contact damage, All the above effects are only active when the item is used for the current room. The beam is piercing and spectral, dealing damage to all enemies and ignoring all obstacles in its path. When you take the reverse path back up to Home, the trinket will turn into Cracked Key in the same floor/room you dropped it before. Harn 1.00 ms de dao y tendrn 5.25 ms de rango que las lgrimas normales disparadas por el ojo derecho. (6 full hearts to fully charge), Unless fully charged, hearts picked up are consumed by the Alabaster Box, instead of being added to your life total. item room pool, red, boom, tnt, * item room, treasure room, item room pool, wooden, cross, brown, Isaac can now hold two trinkets at the same time, Drops a random trinket on the floor when picked up, Allows you to pick up more trinkets while also holding The Tick, * shop room pool, shop item pool, purple, pink, bag, All of Isaac's bombs now leave a poison effect on any enemies within the blast radius, As well as dealing the standard 60 damage for a bomb, it will apply a Damage over Time effect that does 4 or 6 damage per tick, Has a chance to drop from the Super Sloth miniboss fight. The recharge time of this item depends on the Rune/Soul Stone held: 2 rooms: Rune of Ansuz, Rune of Berkano, Rune of Hagalaz, Soul of Cain, 3 rooms: Rune of Algiz, Blank Rune, Soul of Magdalene, Soul of Judas, Soul of ?? Enemies touching the head don't hurt Isaac, UNLOCK: Unlock this item by defeating Delirium as Tainted Forgotten, Item Pool: Boss Room, Crane Game, Golden Chest, Drops 1 random rune or soul stone when picked up, Item Pool: Shop, Golden Chest, Mom's Chest, Old Chest, Tears have a chance to become a tooth, dealing x3.2 damage, similar to Tough Love, The chance to fire a tooth with this trinket is affected by your Luck stat, At +0 luck you have ~12% chance for this effect to activate, At +9 luck every tear you fire will be a tooth, Chance to spawn half a soul heart when picking up a coin, The chance scales up based on the coin's worth: Penny = 16.66%, Double Penny = 30.5%, Nickel = 59.7%, Dime = 83.3%, UNLOCK: Unlock this trinket by defeating ??? increased tears stat does not reduce the charge up time of Brimstone. If you have 1 or less heart containers, this pill becomes Health Up, Hematemesis - Empties all but one red heart container and spawns 1-4 red hearts on the floor. Based on the Steam Workshop mod created by Ink Tears, UNLOCK: Unlock this item by having two items or effects that grant homing shots at once (e.g. Sad Bombs: Bob's Brain will fire tears upon exploding. Little Gish Little Steve The Relic The Halo Money Equals Power Blood Bag Odd Mushroom (Thin) Odd Mushroom (Large) Whore Of Babylon Bucket Of Lard Stat Down pills do nothing, and items like Experimental Treatment increase stats but don't reduce any, This effect works on items that apply negative stat modifiers, such as Soy Milk, This effect works for anything that gives temporary buffs, like Devil/Strength cards, or kill bonuses like Bloody Lust, If you somehow lose Rock Bottom, your stats will go back to normal, UNLOCK: Unlock this item by defeating the Boss Rush as Jacob & Esau, Bombs now explode with a random effect (e.g. Doesn't include Curse Room doors or spiked rocks, Tears can be controlled mid-flight using the directional keys, In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him, Fully heals all your red heart containers, Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it, The visual effect is similar to the effect given to tears by the GodHead item, The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac, In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect, The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades, Upon taking damage, you have a chance to dislodge the spider from your face. Each room is locked to a specific trinket effect, meaning if you exit and re-enter a room, that specific room will always have the same effect. Platelets travel to the site of the injury. The familiar uses Isaac's tears, range, shot speed, and tear effects, and deals 0.35x Isaac . UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lilith. Todas las lgrimas disparadas por el ojo izquierdo sern de color rojo. This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. Each brimstone laser deals 8 damage per tick for 13 total hits. shop item pool, brown, x, cross, paper, Isaac has a random chance to fire another tear out the back of his head, The chance to fire the second tear can improve based on your luck stat and will always activate at +5 Luck, At +0 luck theres a ~50% chance for this effect to activate, Synergizes very well with a lot of items. Completion Marks +1 flat damage. smile, lil' brimstone, Prevents Isaac from taking any damage, but instead summons a familiar heart that follows you around. Displays a random cryptic message on the screen similar to the fortune machine ones. white, red, pink, When used, slows down all enemies in the current room and their projectiles for about 8 seconds, * item room, treasure room, item room pool, hour glass, hourglass, egg timer, sandbrown, glass, A familiar which follows Isaac around and shoots blood tears that deal 5 damage, The tears appear red but have no additional damage, Sister Maggy fires tears at a rate of 1 tear per second, REPENTANCE - Sister Maggy's tear damage has been increased to 5 (from 3.5), to match its original Flash damage, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red, dead, baby, Isaac's tears are replaced with a laser that has unlimited range and can only fire at right angles, Lasers travel through enemies but not obstacles in the room, Synergizes with most items that affect how many tears you fire (20/20, Mutant Spider etc.) Teratoma, Envy) then Meat Cleaver will deal a lot of damage and trigger the splitting effect, If the split enemy has low enough health, it will just die instead of splitting, Doesn't work on end-game bosses except Delirium, where it will deal a chunk of damage and spawn a 2nd Delirium to deal with, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Isaac, You no longer take damage from poison/toxic gas/burn effects, and become immune to fear/confusion, This item isn't available in any item pools - you are automatically given it after defeating Dogma, just before The Beast sequence, Grants a one-time use of the Holy Mantle effect, On normal mode this grants The Wafer effect, causing all damage to do a maximum of half a heart each time, Sets your health to 6 hearts if you have fewer than 6. Deals 45 damage to enemies it lands on. Chocolate Milk - Charge time is reduced and the eye starts flashing after 2 seconds of full chocolate milk charge, giving larger tears. This tear turns enemies to gold for a few seconds and causes them to drop 1-4 coins if killed while golden (similar to the Midas' Touch item), When the Midas Touch tear effect triggers, it will remove 1 coin from your current total, The golden tear deals double your tear damage, The effect can still trigger even if you have no held coins, UNLOCK: Unlock this item by defeating Greedier Mode with Keeper, Doubles the effect of most tarot cards. When an enemy touches the halo for couple of seconds, a beam of light will come down and deal a burst of damage to it, The triggered beam also fires in all 4 cardinal directions, dealing damage to anything it touches, Every time Isaac takes damage, the halo grows slightly bigger up to a maximum of 10 times. Transformations and IBS also have special effects: Stone Dips deal 3.5 more damage and can take 6 hits before they die. Maggy - +1 HP up. You still take damage however when using Blood Donation machines and Devil Beggars, *, spikes, spikey, spike rock, greyhost, grey host, Causes all pedestal items to show up as rotating items, that swap every 1 second between the original spawned item and a HP up item. chalice, indiana jones, * angel room pool, god room pool, angel room item, bird, white, Every time you use this item it deals 40 damage to all enemies in the room and Isaac also takes damage, The first use per room takes 1 full heart, then 0.5 hearts per use after that, Shields and invincibility effects do not prevent damage when using this item, Using with Isaac's Heart previously prevented you from taking damage, however in Repentance this was fixed, Using this item as The Lost will instantly kill him, even if you have Holy Mantle active, UNLOCK: Unlock this item by beating Satan with Samson, * item room, treasure room, item room pool, razor, straight, edge, barber, bloody, brown, silver, Follows behind Isaac and can be swung back and forth, dealing 5 contact damage per tick to anything it hits, Every time the hairball kills an enemy, it grows in size allowing it to deal more damage, This is one of the items which allows you to transform into Guppy, Moving to a new floor decreases the size of the hairball, * devil pool, devil room pool, devil deal, grey, brown, pile, guppys hairball, guppy hairball, A familiar that mirrors the player's movements and shoots tears directly at Isaac, Abel's tears do 3.5 damage, unless playing as Cain in which case they do 5, REPENTANCE - Abel now has an increased rate of fire, and will mirror to the other side of the room, even if it's off screen. The room doors will open if only frozen enemies remain, UNLOCK: Unlock this trinket by defeating challenge #41 (Pica Run), Every time you kill an enemy you get an invincibility shield for 1 second, While shielded, each enemy killed adds +1 seconds to the duration, UNLOCK: Unlock this trinket by defeating challenge #37 (Bloody Mary), * item room, treasure room, item room pool, green, cry, plant, Tears now shoot three at a time (Triple Shot). UNLOCK: Unlock this item by defeating Mother in the Corpse II as Eve, When used, this item does a shout-type attack, with its effect increasing in damage and size the more charges you have, Larynx can be used with any number of charges. Monsters Binding of Isaac: Rebirth Wiki is a FANDOM Games Community. Brimstone is a promotional cosmetic item for all classes.It is based on the horns given by Brimstone in the video game The Binding of Isaac: Rebirth; a pair of curved horns.. Increases the maximum heart limit to 18. 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