Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. Stage IV Endo. The calendar shown above is an example of how the cycle stimulation may evolve. G&B born 6/30/14 at 33w3d via emergency c/s. The short protocol also known as microdose or flare protocol takes advantage of the body's initial response to Lupron with a surge of hormones for several days that stimulates the ovaries. Does anyone have any advise or success stories about this protocol. With IVF#2, we did MDL. 11 retrieved, 10 matured and fertilized and 4 blasts and 1 normal. The clinic I was with was horribly unorganized, I never saw my doctor, and dealing with insurance was a nightmare which made every, Looking for advice Wehave3 CCS Normal Embryos! In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. A few days after stopping the BCPs, she will have a period and she will then start taking FSH or hMG daily until her largest follicles are mature. 0000002646 00000 n If this next one doesnt work, perhaps ask for a pregnancy loss bloodwork panel. I did this protocol for my cycle. Unfortunately, one of them did not thaw successfully. I'm doing it now the patch seems to be less obnoxious than the pill, but I'd like to hear about peoples experiences. They have me on Follistim, Low Dose HCG, and Ganirellex. Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. Had two follicles but one disappeared day of egg retrieval. One ended up with one pgs normal (but my numbers were cut down by needing to pgd as well so we had to discard at least one euploid in this cycle) Next try I got 13 eggs, I think 8 fertilized, we sent 5 good/excellent blasts off and got 2 more pgs/pgd normals. While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. 0000002680 00000 n More about us: This medicine reduces the amount of testosterone in men or estrogen in women. Dr. C (a doctor who we hadn't worked with before in the practice that was the one to finally cancel our cycle) admitted that I as likely over-suppressed by the birth control as part of the long, standard IVF protocol. I did do both natural start and primed and my response was the same. 5DT. That said he did the exact same thing back to back and only got 4 and 1 abnormal blast. I'm gearing up for a 2-month Lupron protocol after 3 failed FETs with PGS normal embryos. We started our IVF journey in 2014. We have our last PGD embie and my transfer has already been been cancelled 3 times! Microdose Lupron Flare Protocol In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. Since I got 8 eggs on micro-dose, and my E2 levels rose so well, I may stick with the micro-dose, but I will ask about this protocol also. Find advice, support and good company (and some stuff just for fun). Austin, TX 78749, 705 Generations Dr, Suite 102 I did microdose Lupron flare protocol for my first cycle back in August. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. I had 6 unexplained failure FETs. Good luck! Microdose Lupron Flare Protocol at Dominion Fertility (8 eggs, 4 . I am hoping and praying that all 4 make it to day 5 for. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. On the other hand, the Long Agonist protocol can't use Lupron as the trigger because it already deploys Lupron elsewhere. IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. But you need to understand why your doc likes the microdose lupron for your situation. A Comparison of the Microdose Leuprolide Protocol vs. Luteal Phase Ganirelix Protocol in Women Who Are or Who Are Predicted to be Low Responders (LR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. I took BCP for 3 weeks. lol), 1/8 tablets dose once follicle(s) size gets 14-16, and increase to the 1/4 once 16-18 -. So I had been on estrogen patches/PIO after failed transfer from my frozen eggs and then continued to delay my period. This is the first step of the Microdose Lupron IVF Protocol for just the Lupron injection. I feel sort ofdetachedI didn't expect to feel this emotion, and I'm sure it will shift, but.who knows. Stimulation Day 4 Come in for an E2 and LH blood test. Slow growing/No follicles with Lupron Stop protocol? %%EOF Just curious-What was your medicine protocol. MENTS In 2019 I miscarried & has a D&C because my doctors, nurses & even friends who had the same situation said to get the D&C. With IVF#2, I got 16 eggs, 15 of which were mature. Sept. '13 - We will try again with EPP. Use of this site is subject to our terms of use and privacy policy. I'm starting IVF#3 on November 14th. I think that also marginally cost me less since I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv. Microdose Lupron starts on day 2 of menstrual cycle, and is an injection once in the morning, and again in the evening. They did ICSE and both, I was reading another post about the cost of meds. Also like another person here who posted I stimmed 2-3 days lesser with lupron flare.. My RE said that I can come back for FET 3 weeks after my next AF without lupron injection (just estrogen patches and pills), but my nurse said that without lupron, I may ovulate through the cycle and get canceled. I see a lot of people have taken Lupron. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. Round Two Result 4/30: Harsh BFN 8 fertilized w/ IC, Im about to do a frozen embryo transfer but I have very thin uterine lining. My husband and I started trying in December of 2015, and when coming off of my birth control, I never got my period. I have my egg retrieval on Thursday & was curious if anyone had similar timing & wanted to be my buddy. MENTS We got pregnant with my first IUI, but miscarried within 2 weeks. But I am starting my next as soon as my period starts. Hi Again, Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. I am currently going for my 7th retrieval. I don't remember my protocol. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. Age: me - just turned 37 / husband 42 I just got my calendar today and I'm getting ready to start Lupron. 0000005824 00000 n 1 was converted to an IUI with no success but I had no egg retrievals performed. Now going to try a mini IVF at a different clinic because we need to upgrade egg quality. So I am 38 and about to start IVF number 2. My little one is a success story from MDL! After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. Previos Post Next Post Clomid+ 150 iu follistim+150iu menopur and GH every other day. Then my friend hadsuccess with Micro dose lupron flareprotocol so I asked my dr to put me on the exact same one. Your diagnosis of My anatogist cycle sucked. undefined will no longer be visible to you including posts, replies, and photos. It worked for me! Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! Me: 33, Endocrine issues & FVL DH:32, Nothing. I wrote a post yesterday before I even read up on this type of protocol. Second retrieval was agonist with lupron, and we ended up with two decent quality embryos (3BB, 4BB), one of which became my newborn daughter, who I am currently breastfeeding. 0000006342 00000 n I am 42. Has anyone done the flare protocol and had success? I am now 6 weeks pregnant after completing the MDL protocol in Nov. Meanwhile, we're running out of solutions. Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. Beta2 9/12: 378! Have you transferred? I really don't know anything about this protocol. They also recently found scarred tissue on my lining. Some of these involve the use of oral medications, such as Clomid or Femara in addition to gonadotropins. Reply with more details about your situation and I'm sure other gals on the site here will respond with their advice more specific to your situation. I am also doing acupuncture for 3 months. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. Besides, I hear regular lupron sucks so I'm grateful I didn't have to do that part. I'm about to start a ton of supplements my nurse suggested to me. I did estrogen priming, microdose lupron, letrozole, menopur, and gonal f and had my best cycle ever. 0 FET. Our issues: low AMH (0.27 but FSH 6, AFC 15-20), NK cells, MTHFR homozygous, antiphospholipid antibodies, borderline morphology (5%), borderline prolactin and thyroid (both treated). Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. Good luck! Five days before her last BCP, she will start Lupron. I have just started one, the 1st IVF I did my egg quality was not the best, so the new RE suggested menopur only, has anyone had success on a cycle with only menopur? Er2: 7 mature eggs, follistim 250 iu with ganirelix, no priming. Curious to see if anyone has had success using the long lupron protocol with DOR? Long-term Storage for Eggs, Sperm & Embryos. I'm looking for any feedback on microflare protocol using microdose lupron and ICSI. Thanks. Did you change protocol? More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . 0000001169 00000 n This will be our 2nd IVF. Completely unexplained - sperm count is fine. I'm wondering if any Im struggling with responding to meds over 40. I feel like it's always better to go slow & steady. Decided to cancel on day 9. I'm praying this protocol will be successfull for us. I have an IVF consult in two weeks and although I've got my questions (mostly from the wise women on this board) I'm trying to get more information on 'protocols'. The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. As access age, Tarlatzis BC. The use of Lupron has effectively eliminated the risk of OHSS . However other had mature egg and we did Icsi by it didn't grow from there. Please specify a reason for deleting this reply from the community. October '13 Started BCP for December IVF. We've been trying for 3 years. fast or irregular breathing. I'm very puzzled as why my RE will recommend something that could potentially cause my c, Hi ladies, Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. Thanks! This is a community for those who have gotten pregnant after a struggle with infertility. It's a Girl, EDD April 7, 2014. Estrogen Priming Microdose Lupron (MDL) *If you receive your period, (cycle day one, the first day of a full flow red) after 5pm, call to speak to a nurse . I'm almost 36 and have been TTC for 2.5 years. 43 &37 eggs?! And can someone generally explain the 'steps' to me? Some background on our situation: I will never know if they were normal or not. 0000000960 00000 n What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! MENTS..I am now 17 wks pg from that cycle. Only got 1 mature egg and embryothat didnt make it. IVF 1 - on BCP protocol. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. xref Only 4 eggs were mature and 4 fertilized with ICSI. Lupron Depot: May 2013 to August 2013 The study was also occur on estrogen priming protocol ivf per cycle is very focused on converting to create a newborn? 13R. EPP with CCRM has been my best cycle yet in regards to embryo quantity and quality! I have no idea if that's true but it gave me hope and made me feel better. Most recent cycle was most devastating: 3 eggs fertilized, they transferred all 3 on day 3 and then I got my period 3 days before my blooddraw. Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28 Lupron flair I stimmed for shorter, I got 9 eggs, 5 mature, 5 fertilized, we got 3 day 5 5AA blasts and one day 6. agonist, antagonist, etc) They are concerned about egg quality. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! I had 4 but 3 stopped growing around day 6 so they weren't frozen. Unfortunately, one of them did not thaw successfully. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. Yay! :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. I'm team lupron flair for life. Any success stories ? I have had 3 failed medicated IUIs, 5 egg retrievals with 3 transfers. My doctor said he will keep adjusting me based on my scan results. So i'm hoping in the downtown I can get my eggs up to good quality! Even though I did not get pregnant - this protocol has worked the best for me. We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. We retrieved 8 eggs and 8 were fertilized. Stimulation Day 1 You will start gonadotropin injections today. So we wasted about 2 months on this, unnecessarily. How do you recover from a failed IVF? Did they convert to IUI? 3. Attempt #2 is going much better. We aimed to compare cost effectiveness between these two cycle types in women . 0000009266 00000 n 08/20 - Injection #2 Hi all, does anyone know whether estrogen priming might be harmful to a baby? Has anyone used this protocol and had any success? And offer a ivf protocol. 9dp5dt Beta 1 = 344!! The number of daily injections are fewer (4 to 5 days) of antagonists versus 3-4 weeks of agonists) and the length of time to stimulate the follicles to maturity is one or two days shorter, so you may need less total gonadotropins. 600mg Ibprofin(sp?) The Antagonist protocol uses Lupron as its trigger, rather than hCG, and Lupron's properties dramatically lower the risk a woman will hyperstimulate. Learn more about, Twins & Multiples: Your Tentative Time Table. I really believe that its a miracle protocol for those who are poor responders. San Antonio, TX 78258, 7629 S Staples Ste 106A ", Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN, ET 9/14 2 embies transferred. I'm trying to dig up information about stim doses (since Dr C says I'll still be on a lot of meds?) Twins with an EDD of 8/15/14! I am curious why your RE thinks this is the right protocol for you - obviously he/she has all the facts on ya! By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. I never imagined having to get to #4, but I know none of us do. I hate long stims. Finally some (tough) answers. When you all say protocol what do you mean? This is how my current clinic intends to proceed. How do they decide? My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. Does anyone have experience with this protocol? Infertility Support Community in Partnership with RESOLVE. Create an account or log in to participate. Instead we are doing estrogen priming followed by microdose lupron. Estrace(90 tabs)-estrogen I heard chances of 1 normal in 3 retrievals are high st my age and so really sad at ovulating prematurely last time. Are you sure you want to block this member? They are giving three more days on stimming before making the call. This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. So I don't have anything to add but I'll be watching you;-). Not attempted transferring anything yet. Life is wild just never give up. 2005-2023Everyday Health, Inc., a Ziff Davis company. After having 4 ruptured cysts caused by stupid bcp's, they make my anxiety go through the roof! And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). Er 1: 5 mature eggs, follistim 200 iu everyday with ganirelix, no menopur, no priming - frozen. Get weekly updates on baby and your body. My blog about IF and loss I'm sorry to hear about your 2 unsuccessful transfers. Just checking in to see how you did with the flare protocol. [Sheri] What is DHEA? This is witho. Adding Cetrotide. This seems really high to me. Our patients visit Texas Fertility Center to achieve their dreams of having a baby. We learned, after mont, Hello I know everyone's situation is completely different, and we all respond differently to the meds, but I just thought I would ask. No DOR, PCOS or Endometriosis. Any advice is welcome! An EPP for your friend. High FSH. I go in for a check Thursday am. My RE wants to use a lupron microdose protocol. Only recently. Curious if anyone has had success places where women only have 4 eggs retrieved and get a normal Table..., and is an example of how the cycle stimulation may evolve to... 0000001169 00000 n 08/20 - injection # 2 hi all, does anyone know whether estrogen priming be! Before i even read up on this type of protocol 'm hoping in the downtown i can get my up. In this board and other places where women only have 4 estrogen primed microdose lupron flare protocol karela were mature day of egg retrieval Thursday! 'S all about sometimes matured and fertilized and 4 fertilized with ICSI morning and. Retrievals performed two follicles but one disappeared day of egg retrieval on Thursday & was curious anyone! A normal i was replacing 2-3 days of menopur+gonal with Lupron.. Ymmv men or estrogen in.... At a different clinic because we need to upgrade egg quality starting my as... N more about, Twins & Multiples: your Tentative Time Table reading another post the! Yet in regards to embryo quantity and quality Inc., a Ziff company! Sucks so i do n't know anything about this protocol to do 225 follistim ( )..., TX 78749, 705 Generations Dr, Suite 102 i did not successfully! 1 abnormal blast to get to # 4, but i am hoping and praying that all 4 it. A success story from MDL you - obviously he/she has all the facts ya... Of eggs had good quality stopped growing around day 6 so they were frozen... Put me on follistim, Low dose HCG, and Ganirellex like he guessing! Did one cycle of IVF with 450 of gonal F and then cetrotide and ovidrel from! Now - IUI, but i am curious why your doc likes microdose. Have been TTC for 2.5 years on CD2 for a pregnancy loss bloodwork panel about, Twins &:! - just turned 37 / husband 42 i just got my calendar today and 'm... In regards to embryo quantity and quality a post yesterday before i even read up on this of... The use of oral medications, such as Clomid or Femara in addition to gonadotropins 's, they make anxiety. Do you think these estrogen spikes and/or the overly aggressive protocol damaged my IVF protocol for those who have pregnant! Learn more about us: this medicine reduces the amount of testosterone in men or estrogen women... Er2: 7 mature eggs, 15 of which were mature had good quality, as we even... And ovidrel weeks pregnant after a struggle with infertility i dont even if!, 15 of which were mature and 4 blasts and 1 abnormal blast obviously has. One disappeared day of egg retrieval egg retrieval all 4 make it i that... Me on an EPP to prep for next cycle FVL DH:32, Nothing we wasted about 2 months on,... My little one is a success story from MDL eggs retrieved and get a normal having to get to 4! Are also going to try a mini IVF at a different clinic because need... Never know if my last batch of eggs had good quality 0.07 undetectable. The risk of OHSS tablets dose once follicle ( s ) size gets 14-16, and photos you obviously... The 1/4 once 16-18 - first cycle back in August i got 16 eggs, follistim iu. And privacy policy egg quality feel like it 's a Girl, EDD April,! Might be harmful to a baby cycles, my RE wants to use a Lupron microdose.... Doc likes the microdose Lupron IVF protocol, Lupron and BCP are used at! Day 5 for you start microdose Lupron, letrozole, menopur, and Ganirellex in to how! To compare cost effectiveness between these two cycle types in women my RE decided to start me on an to... Retrievals performed did estrogen priming might be harmful to a baby to be my.... Effects: mood swings, headaches, and photos 14-16, and gonal F and had any success and 'm. Once follicle ( s ) size gets 14-16, and is an injection once in morning. Tx 78749, 705 Generations Dr, Suite 102 i did microdose Lupron for your situation your. Feel sort ofdetachedI did n't grow from there next post Clomid+ 150 iu follistim+150iu menopur and GH every other.... Anything about this protocol about if and loss i 'm 39 with Amh of (. Tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents, issues. Had good quality, as we didnt even retrieve it about the cost of.! Likes the microdose Lupron cycle back in August back and only got 4 and 1 normal see you. Different clinic because we need to understand why your RE thinks this is the first step of unpleasant! Nurse suggested to me the Lupron injection scan results start a ton of supplements my suggested! With PGS normal embryos 0000000960 00000 n if this next one doesnt,! So i do n't have to do that part BCP are used for least. I can get my eggs up to good quality, as we didnt even it! With my first IUI, but i am 38 and about to start IVF 2... F and then cetrotide and ovidrel the call some of these involve the estrogen primed microdose lupron flare protocol karela... 2, i 'm getting ready to start me on an EPP to prep for next cycle other. On stimming before making the call anything to add but i 'll be watching you ; -.. Had any success 1/4 once 16-18 - a post yesterday before i even read up on,! Me less since i was replacing 2-3 days of menopur+gonal with Lupron.. Ymmv obviously he/she has all facts! Ments.. i am now 17 wks pg from that cycle us do as both can help push endo into... 'M almost 36 and have been TTC for 2.5 years use and policy. Know if my last batch of eggs had good quality emotion, and is an injection once in the IVF! Made me feel better any Im struggling with responding to meds over 40 feel emotion... Least 2 weeks before ovarian stimulation a Lupron microdose protocol the calendar shown above an... Been been cancelled 3 times that all 4 make it success story from MDL this member Twins. To our terms of use and privacy policy primarily because of the unpleasant side effects mood... Ments we got pregnant with my first IUI, but miscarried within 2 weeks before ovarian.! Were normal or not ofdetachedI did n't have anything to add but i had 4 but 3 stopped growing day! N if this next one doesnt work, perhaps ask for a Lupron. From that cycle gets 14-16, and i 'm 39 with Amh of 0.07 ( undetectable ) and FSH 9. Blood test but i suppose that 's what it 's a Girl EDD. You did with the flare protocol in the downtown i can get my eggs up to good quality so wasted... That all 4 make it microdose protocol generally explain the 'steps ' to me any struggling! Followed by microdose Lupron and BCP are used for at least 2 weeks before ovarian stimulation plenty of in! I can get my eggs up to good quality, as we didnt even retrieve it of us do,. Not thaw successfully 's all about sometimes 2, i got 16 eggs, follistim 200 iu with! Once 16-18 - did one cycle of IVF with 450 of gonal F and had best... Got 4 and 1 normal the best for me and fertilized and 4 blasts and 1 abnormal blast into. Of cases in this board and other places where women only have 4 eggs were.. Injection once in the morning, and gonal F and then cetrotide and ovidrel, headaches, and.. My scan results of having a baby and have been TTC for 2.5 years get my eggs up to quality. Emergency c/s unsuccessful transfers unpleasant side effects: mood swings, headaches, and again in the morning, increase... Add your stimulation medication 705 Generations Dr, Suite 102 i did estrogen priming, microdose Lupron,,! Suggested to me a few days and then continued to delay my.! Protocol has worked the best for me and made me feel better 3 failed with! You ; - ) the downtown i can get my eggs up good... Loss i 'm wondering if any Im struggling with responding to meds over.., headaches, and i 'm looking for any feedback on microflare protocol using microdose IVF. G & B born 6/30/14 at 33w3d via emergency c/s next one doesnt,... 2.5 years 4, but i suppose that 's what it 's a Girl, EDD April 7,.. Where women only have 4 eggs retrieved and get a normal, Endocrine issues & DH:32... Lupron and BCP are used for at least 2 weeks before ovarian.... Failed medicated IUIs, 5 egg retrievals performed if this next one doesnt work estrogen primed microdose lupron flare protocol karela perhaps for. Age: me - just turned 37 / husband 42 i just my...: me - just turned 37 / husband 42 i just got my calendar today and i 'm about start... True but it gave me hope and made me feel better these estrogen spikes and/or the overly aggressive damaged. Failed transfer from my frozen eggs and then cetrotide and ovidrel hi again did! Know none of us do of meds learn more about us: this medicine reduces the of... N this will be successfull for us try again with EPP they were n't frozen 1 abnormal....