Due to her age, shes not the best at going outside, but on this pill, she is peeing constantly. Check with your vet before giving your dog any over-the-counter medication, even if it is safe for dogs. Im going to bed. My vet put him on apoquel a 5.4 mg dose split in half twice a day. The new vet recommended apoquel after a while he claimed it had zero side effects and many of his patients said it was a miracle drug. He also had diarrhea and itching. Apoquel is the culprit. I have also found that by wiping his feet with a damp towel after he comes in from outside, there is far less itching and scratching. He is the sweetest pup and has been through so much and I am so frightened that we could lose him next time. This drug should be taken off the market! This was not like her. I hope the drug has not caused this, will see soon what it is. She examined him and told me that he was having a reaction to the hydroxyzine so dont give any more to him. Our vet has him on 3 different medications. Upon returning home from work Gabapentin should start to take effect fairly quickly, and relief should be noticed within one or two hours of administration. A vet gave my dog hydroxyzine because he was licking his paw a lot. He is about 3 yrs old. The mechanism of action is thought to be similar to that of other Janus kinase inhibitors, which block the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response, she says. My 6 year old french bull dog was put on Apoquel on 17/3/17 he had his first seizure on 2/4/17 he passed away on 4/4/17 my dog was fit and healthy up till his first seizure. My dog started taking Apoquel yesterday. In studies, dogs were treated with APOQUEL for more than 2 years. Im not one to complain but, I feel compelled to share our nightmarish experience with this new anti-itching drug called Apoquel. As luck would have it, I did a research on both meds as I normally do with any meds, and as fate would have it came upon this site. Apoquel incidentally never stopped her itching and I will never resume the Apoquel. What are the side effects of hydroxyzine in dogs? Last few days have cut dose in half and itching is still under control. They wont mind! We are going in this evening to put him to sleep. I took her off Apoquel a few days ago.. And had blood work done.. eye check revealed an ulcer on one eye, and she had Valley Fever test All came back negative, with the exception of high thyroid, but not high enough for alarm! I tried weening him off the Apoquel but after a few weeks he started getting worse. Were here at the next morning and she seems a tiny bit more alert. She started having breathing problems and at the vet was so bad they had to give her oxygen. So, my point being could this Apoquel be causing her to urinate more frequently (Also, she gets my hubby up sometimes 2 -3 times a night to go pee. I am now convinced its the apoquel. Active and happy. Not taking any chances! Thank you for any help. My husband took him to the Vet for his routine checkup on June 16th, he got a clean bill of health as usual. Gave this med to my 9 year old Rat Terrier.. now she is dead. Apoquel can be used along with: antibiotics antifungals anti-arthritis drugs Theyll be able to help you figure out the best course of action for your individual dog. But it continued, the swelling, around the legs, his body was swollen, around his eyes. The number of these papillomas appeared to be increasing. I have an 8-year-old Shih Tzu who had more or less uncontrollable itching, mostly she would bite at her paws but then the itching became worst all over. By example, many that are on chemo come to us for high dose IV vitamin C (50g-150g/infusion) I read information about the side effects and took him off the medication about a month ago. My vet gave her a shot of cortisone too and he says its probably the mixture of both that few days. You stated this : Nowhere in the FDA stats on Apoquel does it claim that Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. I am taking him off of apoquell immediately. Our girl is a 14 pound Yorkipoo. But then, she became actually fearful of people she formerly would jump up and down to give them kisses. We did try a restricted diet and the diet didnt affect his scratching. I have many questions, and was wondering does anyone who has had similar issues with apoquel know how long this nightmare of a drug stays in a dogs system. The only thing different in his life has been the apoquel! animals own cells. I didnt get a refill. Recently we moved to a different side of town in a metropolitan area and needed to find a new vet. we didnt have fleas. If not Im going back to the vets. Question: Can My Dog Take Apoquel And Zyrtec Quick Answer: Can Dogs Take Zyrtec Hydroxyzine And Apoquel Together Question: Can Give Dogs Zyrtec Question: How Much Zyrtec Give Dog Is It Safe To Gove A Dog Zyrtec And Apoquel Can U Give Dogs Zyrtec Can Zyrtec Give Dogs Diarrhea Miscellaneous Travel Tips During Covid 2022 Tips for Bike tour in the USA She was starting to feel a little better we thought but then she died the day after Christmas 2016. Apoquel is an allergy medication while Benadryl is an antihistamine. Please read and research this drug before giving it to your dogs. We will look at these later in this article. A couple of weeks later, she called me and talked me into starting him on 1/2 dose as the hydroxizine wasnt working. But, Cytopoint isn't a chemical, like most drugs we're familiar with. This morning I gave to him for a second time. She will pay for it! Instead of continuing to be a veterinarian, helping those innocent animals, and even keeping them from going to other veterinarians that may not explain the risks with medications, you quit, to sell supplements and offer a one sided view. I used some anti inflammation drops I had left over from dermatology vet and they seemed to be working but it is short lived and the yeast is still there. When we returned home he had trouble climbing the stairs.The next morning he couldnt walk. Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. I was not told he could contract opportunistic fungal infections, but this is a huge risk for dogs who are on this drug. The Apoquel was started end of May. Ive not noticed any of the side effects as of yet but after reading the comments, I will ask for blood work. 1,2 The #1 prescribed medicine for allergic itch in dogs. DO NOT GIVE THIS MEDICINE TO YOUR ANIMAL. Early Tuesday Nov 21 my husband woke me up to tell me that Ginny had let put a help and was very weak and could not stand up on her own. Do not use in breeding, pregnant, or nursing dogs. Steroids side effects include CHF, pancreatitis, immunosuppression among many others. I am so worried about my wee guy. My supplement, Ultimate Canine Health Formula contains bovine colostrum in adequate levels for your dog. I was too afraid so I gave her 1/2 dose and I thought she had a mild shake. Both dogs are back to normal and learning to like the regular baths, (with at treat at the end). Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. Thank you all for sharing. My dog has severe allergies and has been under treatment by a dermatology vet for almost two years.. After switching up his allergy shots and exhausting medications including steroids she put Ollie on app quell.. Low numbers of dogs in the studies developed demodicosis, neoplasia, pneumonia, bloody diarrhea, skin and ear infections . Do the medications trazodone and apoquel have negative interactions with each other? Your vet will determine which form will be the best way to treat your dog. It has a different mechanism of action than steroids, cyclosporine, antihistamines, allergy shots and sublingual immunotherapy. He is now getting allergy shots and well see how it goes. In the summer when his allergic signs are more common, I am bathing him twice a week. I feel this drug should not be available. The only thing the bw showed was that his body was basically starving. If you've a medium or small-sized pup the . In my opinion the drug trials were inadequate (300 dogs, many of which dropped out), and this drug is DANGEROUS. Since it is a short-acting drug, the effects will be gone in 24 hours; however, the medication may last longer in dogs with renal or liver impairment. so I went back to my regular vet I trusted who pit Ollie on ever increasing steroids to try to kill this yeast infection. I searched apparel and found that this was a side affect. Fingers crossed she wont have any lasting problems from this drug. Apoquel wont work for my pin , her itching decreased, but never stopped, and it has side effects. Dogs on Cytopoint typically need injections every four to eight weeks. Dogs under one year of age should not take Apoquel. Both drugs are available in pill form, so it is easy to give them to your dog together. Our vet suggested it for our 4 yo GSD to control itching due to an unknown allergy. Let him know that I would never give this precious dog any medication without our friends permission. We actually had to feed her out of our hand or put the food on he floor because I think she was afraid of Apoquel in her dog bowl ( yes I believe pets are smart line this). So, does Apoquel stop itching? Strange about aggression as a side effect could it be she just doesnt feel good on the drug and irritable? Here is a link to the 2011 Study: http://creative.advanstar.com/mkdv/2011/mkdv_vetbenchmarks_email0811/images/VBMZ300_preview.pdf. We again returned to the center on April 30, 2018 to evaluate but left only with another prescription for Apoquel for $138.60. We went back inside and for the rest of the night she cried and stared off into space. THIS DRUG KILLED MY DOG. Seonaid, what dose are you giving your westie? Dogs treated with Apoquel works within four hours, controls allergy itching within 24 hours, and is safe for short-term and long-term usage. I hope you dont still practice medicine. He seemed afraid to move, as if it caused him pain. This may inform but seems to be a scare tactic to sell his products. If that was my dog, I would NOT ever give him those pills. Beware aspergillosis infections due to Apoquel Everyone! On nights 22, 23,25 she had huge seizures, the first waking me with loud howling and all ending with her peeing. We tried Benadryl, Temaril-P & homeopathic remedies. Oh and she totally ripped a couch pillow to shreds while we were out.. a couch she NEVER goes near! Im at the end of the road here in my hopes for Ollie to be healthy. Apoquel is the only thing that has worked. But by God she earned it become i g a vet is harder than med school Lastly, always check with your veterinarian before giving your dog any new medication, just to be on the safe side. We give her oatmeal baths and it dont help. And Grandpuppy has a history of urinary tract issues, but after starting Apoquel her urinary tract problems are blamed on it by her owner. On the sixth day he could barely walk and we took him to an emergency vet hospital. The answer is yes, your dog can take Apoquel and Hydroxyzine together. After taking my 4yo Yorkie off Apoquel 2 weeks ago, (see my comment on 8/21) my girls UPC and albumin have greatly improved. Apoquel helps him -100%, bur increase thirst and he urinated more often then normally. So, if your dog is pregnant it would be wise to discuss this with your vet. If your dog has any of the following, taking antihistamines is not usually recommended: There is also not much evidence regarding the effects that antihistamines have on a pregnant or breastfeeding animal. Thank you for your generosity of spirit and your willingness to share your knowledge and information in an effort to help prevent harm to our innocent companion animals! Unfortunately the itching has started back up. I do not recommend this medication. it may even exacerbate cancer, Diarrhea, vomiting, (both w/ NONE OF THESE SO-CALLED VETS EVEN I am looking for suggestions on what to do. The answer is: it depends on the weight of your dog. The vet never explained the side effects so I am thankful to you very thankful. Sick part about it is I believe they make this drug for people too. In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. All dogs itch sometimes, but when you notice it happening more and more, it could be a sign of a medical condition. Its crazy how fast that can happen. Or, where on the site do you file a complaint? It was a blistery, painful looking infection. He has always had allergies, some seasons are worse than others. Today Im contacting the FDA to self report these side effects. She was totally out of it. On day 19 and 21 i noticed she peed the bed when Id been out(never ever done that before) Read about the JAK inhibitors that protect your dog from developing immune diseases, these inhibitors PROTECT your dog, this drug turns them off. dogs to infection, inflammatory disease demodex mites, and Within the first 12 hours he developed runny poop and lethargy. Pruritus is often the result of allergies, infections, or parasites. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. He came to us with terrible skin allergies. I brought her home and gave her 1 dose of 16 mg around 4PM. The most common side effects were: (2023), Are Catalpa Trees Poisonous to Dogs? start with the lowest possible dose and increase gradually if needed. Thats terrible! Your article leads people like Lynn with the yorkie to jump to blaming Apoquel for her dogs health issues with nothing to substantiate her claim. I always use salt water and E5 cream or take him to the sea side so he can put his paws in to the sea and it worked late time. See more at: http://news.zoetis.com/press-release/investors/zoetis-reports-fourth-quarter-and-full-year-2014-results#sthash.hYHWSMPk.dpuf, Revenue of nearly 5 billion dollarsa pretty heft marketing budget, along with an endless array of paid consultants/lobbyists to ensure that governing bodies dont over regulate and allow the company to keep on selling drugs, regardless of the occasional dead dog. I encourage each and every person considering apoquel to make sure you are educated. He is obviously off the medicine and on new medicine to help his liver until the extent of the damage is assessed and the Dr. can provide a treatment plan moving forward. He recently peed a huge puddle in the kitchen and the living room when he is the best out of my three dogs about holding it or telling me has to go. I am grateful for tis kind of forum to be able to figure out what is wrong with our dog. The treatment can be very effective. Eating and drinking well but started soiling in the house. Do I Have to Stop Minoxidil Before Hair Transplant? company and they said no connections. Xylitol is extremely toxic, even deadly, for dogs. She went from a healthy dog to a dog that was incontinent, drinking lots of water, getting us up in the night to go outside. She ended up on 2 antibiotics and eye drop for 3-4 weeks. Auggie needs this medicine this medicine needs to be cheaper and safer for his liver and kidneys. Remember just a 1/4 or less amount that a human would take for the vitamins unless I mentioned an amount the vet gave me. He also gets half a Zyrtec morning and night. my point is for 3 yrs she had to be kept on prednisone and antibiotics. After two trips to the vet, then being referred to a specialists, we learned his liver enzymes were off the charts. It takes away the itching, but doesnt last for a full day. You may stop using medications all together. Dogs are able to take hydroxyzine. No more Apoquel for my dog! How long can my dog use Apoquel? dog? No more for my precious girl! My miniature schnauzer had the uncontrollable itchiness and smell that went with it. Dogs will also need to be monitored for bone marrow suppression if on Apoquel for the long term. He was on it 1 week and he started terrible diarhea in my house and outside. Antihistamines are over-the-counter so they have a . Liver counts are high is some areas so we will check again in two months. After just a few days the panting and pacing was constant, she never stopped and didnt sleep. 2 packs of apoquel tablets He had pancratitis attack 2 yrs ago, so they do not want to give him prednisone alot. Quite a misleading article. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. I cooked for him for 8 years because he wouldnt eat dog food. APOQUEL (oclacitinib) manufactured by Zoetis, After the allergy tests I gave him Natural Balance Sweet Potato and Fish, which he doesnt eat much so I add other things to it. For the prescriptions !!! Since August 2018 when we discontinued giving Aries Apoquel, there are a few papillomas of small size but nothing like was spreading all over his body. After 5 days on document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Dogsnet is a participant in the Amazon EU Associates Programme, an affiliate advertising programme designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.co.uk Dogsnet is also a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Veterinarian, author, advocate for alternative, natural solutions for dog and cat health, Dr. Andrew Jones, DVM Working very well for paw licking, but like others, he has to pee all the time and did so in the house yesterday (something he NEVER does). Ollie is a sweet beautiful springer spaniel. The neurologist said by default he had to dx her with epilepsy. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of APOQUEL. This is sad. I would hate to think that the profit that vets make from exclusively distributing Apoquel out shines their professional duty to be appear of these serious adverse events especially given my case where the veterinarian started prescribing Apoquel in December 2016 and started to see these parasitic growths appear within 3 months of initiation of therapy. He has had two seizures which he has never had his whole life. We are going to wean her off the supply we have and tell the vet we are going to take her off the apoquel. Hydroxyzine for dogs is a canine antihistamine. Anything that prevents the immune system from functioning properly is dangerous. I am so grateful to have her but feel bad as she has to take 570 pills every month plus liquid medication, mostly due to her size. And one last comment, you claim that Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. As a result, hydroxyzine pamoate is what doctors will prescribe to human patients to treat anxiety. The hot topic in the world of dermatology right now is Apoquel.Apoquel is an exciting new medication for the treatment of allergic itching in dogs. Seems Im out $147 for a month supply. The answer is no. Here are my 7 most important natural remedies you should be considering: Im wondering if anyone has had luck with a very low dose achieving less itching with less side effects? CET chews with a bacteriostat impregnated. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. It has been the Apoquel doing all of this, I believe. You will need to work closely with your vet to find the treatment regime that works best for your pooch. The first day I thought he had something stuck in his throat but since then it hasnt stopped so here I am I decided to look up the side effects and found this site. Also, the little guy was not scratching. My dog died this past Sunday and had all of the Symtoms I have seen in most of this comments, he was clumsy and peed in weird places out of nowhere I knew what my dog ate and how heathy he was until this drug was giving to him. 1 [deleted] 8 yr. ago Two days ago, I woke up in the morning and went to feed by dog and he could not walk or stand. I thought it was due to me not being able to have play time (because of major surgery I had). At this point our cost has been $2200. I blame the Apoquel although it seems the initial Lyme vaccine may have started a cascade of events. How to Report Apoquel Side Effects in Dogs Apoquel side effects in dogs can be reported directly to the manufacturing company. Total bill for this visit was $309.95 of which $126 was for another Rx for 70 Apoquel 5.4mg, Over the following months, we started to see these growths appearing all over his body that appeared to be papillomas (warts) in addition to having interdigital cysts between his toenails causing him to constantly chew/lick them to the point of becoming scabbed. A. lethargic, depressed, doesnt want to drink out of water bowl (to scary), peeing in the house, cant see, everything is scary because of vision issues, and I suppose the greeting people is a result of just not seeing who or what it is! Her side effects seem to be aggression toward new dogs she meets and coughing. The internist believes that continuing the Apoquel any further (would) wreak havoc in his immune system, that we can only expect more papilloma lesions, further inflammation of his lymph nodes, lower platelet cell cell count and so on.". She was still eating and seemed a little more tired so I wasnt alarmed. But I will never use these medications again and will find alternative methods of controlling the infections, i.e. We had tried everything, including allergy shots. But, sometimes this is the desired outcome. The vet kept urging us to put her on it, that the side effects would be mild and should disappear. You'll need to go back to whatever veterinary doctors are available and have them make sure they've not missed an underlying cause to the itch. In fact, antihistamines are quite often used to treat skin allergies in dogs. The above mentioned worked but she also added Atopica for 3 5 months to sustain the gut so he wouldnt itch anymore. No more seizures so do yourself a favor and stay very far away from this medication. (2023), How Long After Color Remover Can I Bleach My Hair? Just not for any on this wall including mine. I have photos of that food really odd changes!!! I have a St. Bernard Therapy Dog who had allergies, itching ears and feet. I have a 5 yr old Yorkie/Poodle. Her body was like a noodle. He was diagnosed with severe pancreatitis. Let's look at what cetirizine does, what its common side effects may be and in what instances its use is not recommended. Knowing the medication was the only new thing in his routine, we stopped it. I would rather give him zyrtec and deal other ways with his allergies. He is 25 lbs (huge westie, I know), and I have found that if I give him 1/4 pill in the morning that the side effects go away and itching is pretty much under control. Multiple doses of antibiotics for skin infections. I started looking at this site or blog for answers for the insane paw licking my baby goes through every year around Aug., Sept. I put my Labrador retriever on Apoquel and within a day his severe seasonal allergies stopped. Two days ago (45 days into Apoquel) Peatie woke from a nap and walked around frantically bumping into things, hes blind, but it seemed more than usual, so I picked him up and he went tight in my armskind of like a dog stretching, but I soon realized he was in a seizure when he urinated all over me. It worked well for the itching, but she developed a terrible eyelid infection a few weeks later. Drugs.com is where I found all the horrible side effects of the drug and it was too late. I am not a qualified vet or anything, just something I think might be her problem. He now has a tumor on his neck ( just removed and sent for histopatholgy). But not at the cost of seizures. Other than some itching she has always been healthy. I gave him a pill at 9 a.m. yesterday morning and another at 9 p.m. yesterday evening. I just had my 14 year old westie Flo on Apoquel for 26 days. While the drug helped the itching slightly it did not stop it. (Answered 2023), What Are Cat and Dog Paws Adapted for? My vet has referred us to a vet specialist, which I hear is very expensive. Is it okay to take her off immediately, or do I need to wean her gradually? P.S. Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998). The omega 3 dose I suggest is 1000 mg per 10lbs daily- this works out to giving 1 tablespoon of flax per 50lbs daily to your dog. Two days ago he began vomiting, lethargy and dehydration. My dog had a history of pancreatitis, vet should have known this product and think this is not good for this dog. Allergies stopped to Stop Minoxidil before Hair Transplant is: it depends on sixth! 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