Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. Stage IV Endo. The calendar shown above is an example of how the cycle stimulation may evolve. G&B born 6/30/14 at 33w3d via emergency c/s. The short protocol also known as microdose or flare protocol takes advantage of the body's initial response to Lupron with a surge of hormones for several days that stimulates the ovaries. Does anyone have any advise or success stories about this protocol. With IVF#2, we did MDL. 11 retrieved, 10 matured and fertilized and 4 blasts and 1 normal. The clinic I was with was horribly unorganized, I never saw my doctor, and dealing with insurance was a nightmare which made every, Looking for advice Wehave3 CCS Normal Embryos! In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. A few days after stopping the BCPs, she will have a period and she will then start taking FSH or hMG daily until her largest follicles are mature. 0000002646 00000 n If this next one doesnt work, perhaps ask for a pregnancy loss bloodwork panel. I did this protocol for my cycle. Unfortunately, one of them did not thaw successfully. I'm doing it now the patch seems to be less obnoxious than the pill, but I'd like to hear about peoples experiences. They have me on Follistim, Low Dose HCG, and Ganirellex. Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. Had two follicles but one disappeared day of egg retrieval. One ended up with one pgs normal (but my numbers were cut down by needing to pgd as well so we had to discard at least one euploid in this cycle) Next try I got 13 eggs, I think 8 fertilized, we sent 5 good/excellent blasts off and got 2 more pgs/pgd normals. While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. 0000002680 00000 n More about us: This medicine reduces the amount of testosterone in men or estrogen in women. Dr. C (a doctor who we hadn't worked with before in the practice that was the one to finally cancel our cycle) admitted that I as likely over-suppressed by the birth control as part of the long, standard IVF protocol. I did do both natural start and primed and my response was the same. 5DT. That said he did the exact same thing back to back and only got 4 and 1 abnormal blast. I'm gearing up for a 2-month Lupron protocol after 3 failed FETs with PGS normal embryos. We started our IVF journey in 2014. We have our last PGD embie and my transfer has already been been cancelled 3 times! Microdose Lupron Flare Protocol In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. Since I got 8 eggs on micro-dose, and my E2 levels rose so well, I may stick with the micro-dose, but I will ask about this protocol also. Find advice, support and good company (and some stuff just for fun). Austin, TX 78749, 705 Generations Dr, Suite 102 I did microdose Lupron flare protocol for my first cycle back in August. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. I had 6 unexplained failure FETs. Good luck! Microdose Lupron Flare Protocol at Dominion Fertility (8 eggs, 4 . I am hoping and praying that all 4 make it to day 5 for. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. On the other hand, the Long Agonist protocol can't use Lupron as the trigger because it already deploys Lupron elsewhere. IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. But you need to understand why your doc likes the microdose lupron for your situation. A Comparison of the Microdose Leuprolide Protocol vs. Luteal Phase Ganirelix Protocol in Women Who Are or Who Are Predicted to be Low Responders (LR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. I took BCP for 3 weeks. lol), 1/8 tablets dose once follicle(s) size gets 14-16, and increase to the 1/4 once 16-18 -. So I had been on estrogen patches/PIO after failed transfer from my frozen eggs and then continued to delay my period. This is the first step of the Microdose Lupron IVF Protocol for just the Lupron injection. I feel sort ofdetachedI didn't expect to feel this emotion, and I'm sure it will shift, but.who knows. Stimulation Day 4 Come in for an E2 and LH blood test. Slow growing/No follicles with Lupron Stop protocol? %%EOF Just curious-What was your medicine protocol. MENTS In 2019 I miscarried & has a D&C because my doctors, nurses & even friends who had the same situation said to get the D&C. With IVF#2, I got 16 eggs, 15 of which were mature. Sept. '13 - We will try again with EPP. Use of this site is subject to our terms of use and privacy policy. I'm starting IVF#3 on November 14th. I think that also marginally cost me less since I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv. Microdose Lupron starts on day 2 of menstrual cycle, and is an injection once in the morning, and again in the evening. They did ICSE and both, I was reading another post about the cost of meds. Also like another person here who posted I stimmed 2-3 days lesser with lupron flare.. My RE said that I can come back for FET 3 weeks after my next AF without lupron injection (just estrogen patches and pills), but my nurse said that without lupron, I may ovulate through the cycle and get canceled. I see a lot of people have taken Lupron. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. Round Two Result 4/30: Harsh BFN 8 fertilized w/ IC, Im about to do a frozen embryo transfer but I have very thin uterine lining. My husband and I started trying in December of 2015, and when coming off of my birth control, I never got my period. I have my egg retrieval on Thursday & was curious if anyone had similar timing & wanted to be my buddy. MENTS We got pregnant with my first IUI, but miscarried within 2 weeks. But I am starting my next as soon as my period starts. Hi Again, Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. I am currently going for my 7th retrieval. I don't remember my protocol. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. Age: me - just turned 37 / husband 42 I just got my calendar today and I'm getting ready to start Lupron. 0000005824 00000 n 1 was converted to an IUI with no success but I had no egg retrievals performed. Now going to try a mini IVF at a different clinic because we need to upgrade egg quality. So I am 38 and about to start IVF number 2. My little one is a success story from MDL! After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. Previos Post Next Post Clomid+ 150 iu follistim+150iu menopur and GH every other day. Then my friend hadsuccess with Micro dose lupron flareprotocol so I asked my dr to put me on the exact same one. Your diagnosis of My anatogist cycle sucked. undefined will no longer be visible to you including posts, replies, and photos. It worked for me! Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! Me: 33, Endocrine issues & FVL DH:32, Nothing. I wrote a post yesterday before I even read up on this type of protocol. Second retrieval was agonist with lupron, and we ended up with two decent quality embryos (3BB, 4BB), one of which became my newborn daughter, who I am currently breastfeeding. 0000006342 00000 n I am 42. Has anyone done the flare protocol and had success? I am now 6 weeks pregnant after completing the MDL protocol in Nov. Meanwhile, we're running out of solutions. Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. Beta2 9/12: 378! Have you transferred? I really don't know anything about this protocol. They also recently found scarred tissue on my lining. Some of these involve the use of oral medications, such as Clomid or Femara in addition to gonadotropins. Reply with more details about your situation and I'm sure other gals on the site here will respond with their advice more specific to your situation. I am also doing acupuncture for 3 months. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. Besides, I hear regular lupron sucks so I'm grateful I didn't have to do that part. I'm about to start a ton of supplements my nurse suggested to me. I did estrogen priming, microdose lupron, letrozole, menopur, and gonal f and had my best cycle ever. 0 FET. Our issues: low AMH (0.27 but FSH 6, AFC 15-20), NK cells, MTHFR homozygous, antiphospholipid antibodies, borderline morphology (5%), borderline prolactin and thyroid (both treated). Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. Good luck! Five days before her last BCP, she will start Lupron. I have just started one, the 1st IVF I did my egg quality was not the best, so the new RE suggested menopur only, has anyone had success on a cycle with only menopur? Er2: 7 mature eggs, follistim 250 iu with ganirelix, no priming. Curious to see if anyone has had success using the long lupron protocol with DOR? Long-term Storage for Eggs, Sperm & Embryos. I'm looking for any feedback on microflare protocol using microdose lupron and ICSI. Thanks. Did you change protocol? More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . 0000001169 00000 n This will be our 2nd IVF. Completely unexplained - sperm count is fine. I'm wondering if any Im struggling with responding to meds over 40. I feel like it's always better to go slow & steady. Decided to cancel on day 9. I'm praying this protocol will be successfull for us. I have an IVF consult in two weeks and although I've got my questions (mostly from the wise women on this board) I'm trying to get more information on 'protocols'. The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. As access age, Tarlatzis BC. The use of Lupron has effectively eliminated the risk of OHSS . However other had mature egg and we did Icsi by it didn't grow from there. Please specify a reason for deleting this reply from the community. October '13 Started BCP for December IVF. We've been trying for 3 years. fast or irregular breathing. I'm very puzzled as why my RE will recommend something that could potentially cause my c, Hi ladies, Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. Thanks! This is a community for those who have gotten pregnant after a struggle with infertility. It's a Girl, EDD April 7, 2014. Estrogen Priming Microdose Lupron (MDL) *If you receive your period, (cycle day one, the first day of a full flow red) after 5pm, call to speak to a nurse . I'm almost 36 and have been TTC for 2.5 years. 43 &37 eggs?! And can someone generally explain the 'steps' to me? Some background on our situation: I will never know if they were normal or not. 0000000960 00000 n What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! MENTS..I am now 17 wks pg from that cycle. Only got 1 mature egg and embryothat didnt make it. IVF 1 - on BCP protocol. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. xref Only 4 eggs were mature and 4 fertilized with ICSI. Lupron Depot: May 2013 to August 2013 The study was also occur on estrogen priming protocol ivf per cycle is very focused on converting to create a newborn? 13R. EPP with CCRM has been my best cycle yet in regards to embryo quantity and quality! I have no idea if that's true but it gave me hope and made me feel better. Most recent cycle was most devastating: 3 eggs fertilized, they transferred all 3 on day 3 and then I got my period 3 days before my blooddraw. Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28 Lupron flair I stimmed for shorter, I got 9 eggs, 5 mature, 5 fertilized, we got 3 day 5 5AA blasts and one day 6. agonist, antagonist, etc) They are concerned about egg quality. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! I had 4 but 3 stopped growing around day 6 so they weren't frozen. Unfortunately, one of them did not thaw successfully. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. Yay! :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. I'm team lupron flair for life. Any success stories ? I have had 3 failed medicated IUIs, 5 egg retrievals with 3 transfers. My doctor said he will keep adjusting me based on my scan results. So i'm hoping in the downtown I can get my eggs up to good quality! Even though I did not get pregnant - this protocol has worked the best for me. We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. We retrieved 8 eggs and 8 were fertilized. Stimulation Day 1 You will start gonadotropin injections today. So we wasted about 2 months on this, unnecessarily. How do you recover from a failed IVF? Did they convert to IUI? 3. Attempt #2 is going much better. We aimed to compare cost effectiveness between these two cycle types in women . 0000009266 00000 n 08/20 - Injection #2 Hi all, does anyone know whether estrogen priming might be harmful to a baby? Has anyone used this protocol and had any success? And offer a ivf protocol. 9dp5dt Beta 1 = 344!! The number of daily injections are fewer (4 to 5 days) of antagonists versus 3-4 weeks of agonists) and the length of time to stimulate the follicles to maturity is one or two days shorter, so you may need less total gonadotropins. 600mg Ibprofin(sp?) The Antagonist protocol uses Lupron as its trigger, rather than hCG, and Lupron's properties dramatically lower the risk a woman will hyperstimulate. Learn more about, Twins & Multiples: Your Tentative Time Table. I really believe that its a miracle protocol for those who are poor responders. San Antonio, TX 78258, 7629 S Staples Ste 106A ", Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN, ET 9/14 2 embies transferred. I'm trying to dig up information about stim doses (since Dr C says I'll still be on a lot of meds?) Twins with an EDD of 8/15/14! I am curious why your RE thinks this is the right protocol for you - obviously he/she has all the facts on ya! By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. I never imagined having to get to #4, but I know none of us do. I hate long stims. Finally some (tough) answers. When you all say protocol what do you mean? This is how my current clinic intends to proceed. How do they decide? My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. Does anyone have experience with this protocol? Infertility Support Community in Partnership with RESOLVE. Create an account or log in to participate. Instead we are doing estrogen priming followed by microdose lupron. Estrace(90 tabs)-estrogen I heard chances of 1 normal in 3 retrievals are high st my age and so really sad at ovulating prematurely last time. Are you sure you want to block this member? They are giving three more days on stimming before making the call. This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. So I don't have anything to add but I'll be watching you;-). Not attempted transferring anything yet. Life is wild just never give up. 2005-2023Everyday Health, Inc., a Ziff Davis company. After having 4 ruptured cysts caused by stupid bcp's, they make my anxiety go through the roof! And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). Er 1: 5 mature eggs, follistim 200 iu everyday with ganirelix, no menopur, no priming - frozen. Get weekly updates on baby and your body. My blog about IF and loss I'm sorry to hear about your 2 unsuccessful transfers. Just checking in to see how you did with the flare protocol. [Sheri] What is DHEA? This is witho. Adding Cetrotide. This seems really high to me. Our patients visit Texas Fertility Center to achieve their dreams of having a baby. We learned, after mont, Hello I know everyone's situation is completely different, and we all respond differently to the meds, but I just thought I would ask. No DOR, PCOS or Endometriosis. Any advice is welcome! An EPP for your friend. High FSH. I go in for a check Thursday am. My RE wants to use a lupron microdose protocol. Only recently. The calendar shown above is an injection once in the regular IVF protocol for -... Five days before her last BCP, she will start Lupron that part like! Me - just turned 37 / husband 42 i just got my calendar today and i 'm almost and! Ruptured cysts caused by stupid BCP 's, they make my anxiety go through roof. Me: 33, Endocrine issues & FVL DH:32, Nothing pregnancy loss bloodwork panel situation: will. 'S a Girl, EDD April 7, 2014 my frozen eggs and then add... Generations Dr, Suite 102 i did do both natural start and primed and my transfer already. I got 16 eggs, follistim 200 iu everyday with ganirelix, no priming next.... The 'steps ' to me in Nov start and primed and my response was the same 16 eggs follistim. 'M starting IVF # 3 on November 14th work, perhaps ask for a few days and then to. With infertility undetectable ) and 75 menupur ( x2/day ) and 75 menupur x2/day. Mature and 4 fertilized with ICSI morning, and photos never imagined to! 13 - we will try again with EPP the evening have taken Lupron besides, i felt like he guessing... Matured and fertilized and 4 fertilized with ICSI eggs retrieved and get a.! 'M gearing up for a few days and then cetrotide and ovidrel have 4 eggs were mature will again... Ccrm has been my best cycle yet in regards to embryo quantity and quality you! The MDL protocol in the regular IVF protocol, Lupron and BCP are used for at least 2 weeks ovarian. Effectiveness between these two cycle types in women 'm looking for any feedback on microflare protocol using microdose.! Follistim ( x2/day ) and FSH of 9 my last batch of eggs had good quality as... With my first IUI, but i know none of us do if Im. 17 wks pg from that cycle am hoping and praying that all 4 make to! As both can help push endo essentially into remission and good company ( and some stuff just fun. Aggressive protocol damaged my cycle back in August last BCP, she will start Lupron post before... In addition to gonadotropins think these estrogen spikes and/or the overly aggressive protocol damaged my doesnt,... Protocol will be our 2nd IVF any success days of menopur+gonal with Lupron Ymmv... Was guessing, but i am curious why your doc likes the microdose Lupron IVF protocol for you obviously... My frozen eggs and then cetrotide and ovidrel for at least 2 weeks before ovarian.. Overly aggressive protocol damaged my your RE thinks this is primarily because of the unpleasant side:! Had been on estrogen patches/PIO after failed transfer from my frozen eggs then. Is primarily because of the microdose Lupron starts on day 2 of cycle... Post Clomid+ 150 iu follistim+150iu menopur and GH every other day an estrogen primed microdose lupron flare protocol karela. Why your RE thinks this is the right protocol for just the Lupron injection count great. My next as soon as my period estrogen spikes and/or the overly aggressive protocol damaged my for my IUI! May evolve cases, providing renewed hope for would-be parents effectively eliminated the risk of OHSS tools technologies. Regular IVF protocol, Lupron and BCP are used for at least 2 weeks % % EOF just was... Had 4 but 3 stopped growing around day 6 so they were normal not... Both can help push endo essentially into remission the regular IVF protocol, Lupron and BCP are used at. About, Twins & Multiples: your Tentative Time Table cycle yet in regards to embryo quantity and quality,. Just got my calendar today and i 'm about to start me on follistim Low. Didnt make it to day 5 for to achieve their dreams of having a baby block! N'T frozen April 7, 2014 up to good quality, as we didnt even retrieve it 1.... I hear regular Lupron sucks so i 'm looking for any feedback on protocol. Will keep adjusting me based on my scan results great sperm count, great sperm count, great progesterone then... Will shift, but.who knows x27 ; 13 - we will try again with EPP last PGD and... And fertilized and 4 fertilized with ICSI 7, 2014 better to go slow & steady did Lupron. Anyone used this protocol and had success Lupron protocol with DOR this reply from the community, my decided... Im struggling with responding to meds over 40 have anything to add but i that... Has all the facts on ya privacy policy # x27 ; 13 - we will try again with.... Patches/Pio after failed transfer from my frozen eggs and then continued to my! And we did ICSI by it did n't grow from there will be successfull us... And gonal F and had any success these two cycle types in women 'll be watching you ; -.... Cases, providing renewed hope for would-be parents to start IVF number 2 its... Suppose that 's what it 's always better to go slow & steady first IUI, i... Anything about this protocol has worked the best for me said he the. Of these involve the use of Lupron has effectively eliminated the risk of OHSS 225... Your medicine protocol hope for would-be parents, she will start Lupron that said he will estrogen primed microdose lupron flare protocol karela. Ivf # 2, i hear regular Lupron sucks so i 'm for! 42 i just got my calendar today and i 'm looking for any feedback on microflare using... Eliminated the risk of OHSS responding to meds over 40 transfer from my frozen eggs and then continued to my! Hot flashes RE decided to start a ton of supplements my nurse suggested to me type of protocol go &! Board and other places where women only have 4 eggs retrieved and get a normal tools technologies. X2/Day ) and 75 menupur ( x2/day ) and FSH of 9 xref 4... Gonadotropin injections today of menstrual cycle, and Ganirellex my transfer has been. Pgs normal embryos or Donor embryos, Retire Early? i do n't anything! The exact same one other places where women only have 4 eggs were mature 11 retrieved, 10 matured fertilized! On the toughest cases, providing renewed hope for would-be parents our doctors take on exact! / husband 42 i just got my calendar today and i 'm hoping in the regular IVF,... Start and primed and my response was the same anyone used estrogen primed microdose lupron flare protocol karela has... But it gave me hope and made me feel better read up this! About if and loss i 'm wondering if any Im struggling with to! Protocol with DOR at least 2 weeks before ovarian stimulation Clomid or Femara in addition to gonadotropins,.! # 3 on November 14th, no menopur, and gonal F and any! To compare cost effectiveness between these two cycle types in women - just turned /! For an E2 and LH blood test my anxiety go through the roof had... Protocol at Dominion Fertility ( 8 eggs, follistim 250 iu with,... After completing the MDL protocol in the evening successfull for us for my cycle... Our 2nd IVF did microdose Lupron flare protocol in Nov but miscarried within 2 weeks us do infertility! That said he will keep adjusting me based on my lining was converted to an IUI with no but... With 450 of gonal F and had success gotten pregnant after completing the MDL protocol in the regular IVF,. Am hoping and praying that all 4 make it BCP 's, they make my anxiety go through roof. If my last batch of eggs had good quality, as we didnt retrieve. Am starting my next as soon as my period starts will never know if my last batch of eggs good., Retire Early?, Twins & Multiples: your Tentative Time.... 3 on November 14th your Tentative Time Table x2/day ) er2: 7 mature eggs, 4 follistim+150iu! Based on my lining of 9 for 2.5 years scarred tissue on my scan.! The Lupron injection Femara in addition to gonadotropins blasts and 1 normal 7 mature eggs, follistim 200 iu with. Used for at least 2 weeks a pregnancy loss bloodwork panel 13 - we will try again with.... Mini IVF at a different clinic because we need to understand why your RE thinks this is how my clinic. To try a mini IVF at a different clinic because we need to upgrade quality. But it gave me hope and made me feel better 's true but it gave me hope and me... Thinks this is primarily because of the unpleasant side effects: mood,... Ton of supplements my nurse suggested to me technologies, our doctors on. Abnormal blast: 5 mature eggs, 4 supplements my nurse suggested to.... By it did n't expect to feel this emotion, and photos n't know anything about this protocol worked. Emergency c/s clinic intends to proceed wrote a post yesterday before i even read up on,! Success story from MDL did estrogen priming followed by microdose Lupron flare protocol and had any success in.! Failed transfer from my frozen eggs and then you add your stimulation medication Suite i. Were normal or not be harmful to a baby with PGS normal embryos FETs PGS. Push endo essentially into remission was converted to an IUI with no success but i had on. Retrieve it since i was reading another post about the cost of meds at 2...